Recruitment for this lab has closed.
We are studying mechanisms of asymmetric cell division using C. elegans as a model system. We found that asymmetric divisions are regulated by Wnt signaling and that signaling molecules including ƒÀ-catenin localize asymmetrically on the cell cortex. We also identified a large number of mutants defective in asymmetric divisions and analyzing them to elucidate mechanisms of asymmetric cell division. We would like to recruit those interested in studying asymmetric cell divisions in C. elegans as well as in mammals using knowledge we have obtained in C. elegans. Other proposals related to development of C. elegans and asymmetric divisions in other organisms can be considered. Please visit our home page for details of research and publication in our lab. http://www.cdb.riken.jp/cfd/HP6/index-e.html
Background in cell biology, biochemistry, molecular biology, molecular genetics, and/or developmental biology is required. Experiences in C. elegans are not necessary.
Inquiries should include CV and brief summary of your research, reasons for application, and should be sent to Hitoshi Sawa.
Contact: Hitoshi Sawa
RIKEN Center for Developmental Biology
2-2-3 Minatojima-minamimachi, Chuou-ku,
Kobe 650-0047, Japan