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Dr. Yingzi Yang completed her B.S. degree from the Fudan University in Shanghai, China. She received her research training in the U.S. and studied Wnt and Hedgehog signaling in early limb patterning under the guidance of Dr. Lee Niswander at the Sloan-Kettering Cancer Institute, where she was awarded her Ph.D. in Molecular Biology by the Weill Medical College of Cornell University in New York.
After completing a postdoctoral fellowship in mammalian developmental biology and genetics in the laboratory of Dr. Andy McMahon at Harvard University, she joined the Genetic Disease Research Branch of the National Human Genome Research Institute (NHGRI) as a tenure–track investigator in 2000 and adventured into the field of skeletal biology. She received tenure at NHGRI in 2006 and was head of the Developmental Genetics Section and a senior investigator of NHGRI. She was recruited by HSDM as Professor of Developmental Biology in 2014. Dr. Yang has received several honors and awards during her scientific career.
Dr. Yang has published extensively in professional journals. She serves or has served on the editorial boards of several major journals including Cell Research, the Journal of Biological Chemistry, the Journal of Bone and Mineral Research and the Journal of Molecular Cell Biology. Dr. Yang enjoys and is committed to training students at all levels and introducing them to the excitement and significance of biomedical research. Dr. Yang also serves on many professional research and education committees.
Over the past 14 years, Dr. Yang has made groundbreaking contributions to understanding the roles of Wnt and Hedgehog signaling in embryonic morphogenesis, skeletal biology and skeletal diseases. Her research has successfully bridged discoveries of fundamental mechanisms with characterization and treatment of diseases including severe birth defects, osteoporosis, osteoarthritis and heterotopic bone formation. Her studies have revealed fundamental mechanisms of Wnt and Hedgehog signal transduction and their critical roles in many aspects of embryonic morphogenesis and adult physiology.
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