The biochemical and mechanical properties of the cellular microenrivonment play a pivotal role in shaping various biological processes, including cellular behaviour, development, physiology and pathology. In our laboratory, guided by the concept that 'environment dictates behaviour', we explore how cellular and tissue microenvironments impact the behaviour and fate of cells in the context of organ development and regeneration, using mammalian skin as a model. Our primary focus is on revealing the principles underlying the interactions between tissue stem cells and their extracellular matrix, which instruct these processes. Our ultimate research goal is to define and design the microenvironment to manipulate biological processes from outside the cells.

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