David Kingsley


Dr. David Kingsley grew up in Iowa and received his B.S. in Biology from Yale University in 1981. As a graduate student, he used somatic cell genetics to study receptor mediated endocytosis with Dr. Monty Krieger, receiving a Ph.D. from the Massachusetts Institute of Technology in 1986. In 1987 Dr. Kingsley moved to the Frederick-National Cancer Institute to begin postdoctoral with Drs. Neal Copeland and Nancy Jenkins. There he began applying both classic and molecular genetic approaches to vertebrate morphology using laboratory mice. He subsequently established his own laboratory at Stanford University, where he has worked since 1991 as an Assistant, Associate, and Full Professor of Developmental Biology, and an investigator of the Howard Hughes Medical Institute. At Stanford Dr. Kingsley's genetic studies of classic mouse skeletal mutations identified key signaling molecules and membrane transporters used by vertebrates to control skeletal patterning and susceptibility to arthritis. In 1998, he and postdoc Katie Peichel also began using genetic mapping strategies to analyze the molecular basis of evolutionary change in natural populations of threespine sticklebacks. This work has subsequently revealed detailed genomic mechanisms that underlie evolution of new traits not only in fish, but also in many other organisms, including humans.