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- Monday, March 26, 2018 (Day 1)
- Tuesday, March 27, 2018 (Day 2)
- Wednesday, March 28 2018 (Day 3)

*Selected Talks

Monday, March 26, 2018 (Day 1)

 Registration

9:00 - 9:50
In front of the Auditorium, 1st floor of CDB Building C

 Welcoming Address

9:50 - 10:00

Hiroshi Hamada (Center Director, RIKEN Center for Developmental Biology, Japan)

 Session 1: Maintenance of Tissue Integrity

Chair: Fumio Matsuzaki

10:00 - 10:30
S1-1
Developmental origins, induction processes and unconventional functions of heterogeneous stem cells in the hair follicle

Hironobu Fujiwara (RIKEN Center for Developmental Biology, Japan)

10:30 - 10:50
S1-2*
Defining the stem cell lineages in adult skin epidermis

Aiko Sada (University of Tsukuba, Japan)

10:50 - 11:20
Coffee Break
11:20 - 11:50
S1-3
Dissecting lung stem cells and cancer initiation at single cell resolution

Mark Krasnow (Stanford University School of Medicine and Howard Hughes Medical Institute, USA)

11:50 - 12:20
S1-4
A unifying theory of branching morphogenesis

Benjamin D. Simons (University of Cambridge, UK)

 Lunch

12:20 - 13:20
13:20 - 13:50
S1-5
Dynamical regulation of spermatogenic stem cells in homeostasis and after transplantation

Shosei Yoshida (National Institute for Basic Biology, Japan)

13:50 - 14:20
S1-6
Regulation of homeostasis in mammalian epidermis

Fiona M. Watt (King’s College London, Centre for Stem Cells and Regenerative Medicine, UK)

 Poster Session 1

14:20 - 15:50
14:20 - 15:05 Presenters of Odd numbered posters
15:05 - 15:50 Presenters of Even numbered posters

 Session 2: Sytemic Control and Metabolism

Chair: Sa Kan Yoo

15:50 - 16:20
S2-1
Stress and the developmental origins of longevity

Alex P. Gould (The Francis Crick Institute, UK)

16:20 - 16:40
S2-2*
Dietary control of stem cell division through S-adenosylmethionine in Drosophila intestine

Fumiaki Obata (The University of Tokyo, Japan)

16:40 - 17:00
S2-3*
Systemic TGFβ/Activin signaling governs adaptive metabolic responses to nutrient balances of Drosophila species

Yukako Hattori (Graduate School of Biostudies, Kyoto University, Japan)

17:00 - 17:20
Coffee Break
17:20 - 17:50
S2-4
TBA

Satchidananda Panda (Salk Institute for Biological Studies, USA)

17:50 - 18:20
S2-5
Thermogenic fat in energy homeostasis

Shingo Kajimura (University of California, San Francisco, USA)

18:20 - 18:40
S2-6*
Active hypometabolism in inbred mice as a model of suppressed homeostasis of body temperature

Genshiro A. Sunagawa (RIKEN Center for Developmental Biology, Japan)

 Reception at CDB Salon

18:40 - 20:30


Tuesday, March 27, 2018 (Day 2)

 Session 3: Homeostatic Disorder

Chair: Mitsuru Morimoto

9:30 - 10:00
S3-1
Intrinsic tumor suppression and epithelial maintenance by cell competition

Tatsushi Igaki (Graduate School of Biostudies, Kyoto University, Japan)

10:00 - 10:30
S3-2
The evolving roles of organoids in disease biology

Toshiro Sato (Keio University School of Medicine, Japan)

10:30 - 10:50
S3-3*
Spermatogonial stem cell self-renewal requires telomerase through a catalytic activity-independent mechanism

Kazuteru Hasegawa (Stanford University school of Medicine, USA)

10:50 - 11:20
Coffee Break
11:20 - 11:50
S3-4
Mechanisms of regeneration of the damaged liver

Stuart Forbes (University of Edinburgh, UK)

11:50 - 12:20
S3-5
Distinct genetic pathways govern the emergence of skeletal muscle stem cells and their niches

Shahragim Tajbakhsh (Institut Pasteur, France)

12:20 - 12:40
S3-6*
Studies on skeletal muscle atrophy in space - what zebrafish experienced in a space tour

Atsuko Sehara-Fujisawa (Institute for Frontier Life and Medical Sciences, Kyoto University, Japan)

 Lunch

12:40 - 13:40

 Poster Session 2

13:40 - 15:40
13:40 - 14:40 Presenters of posters with category "A"
14:40 - 15:40 Presenters of posters with category "B"

 Session 4: Cell Lineage and Single Cell Analysis

Chair: Ichiro Hiratani

15:40 - 16:10
S4-1
Spatial genomics and single cell lineage dynamics by seqFISH and MEMOIR

Long Cai (California Institute of Technology, USA)

16:10 - 16:40
S4-2
Whole organism lineage tracing with CRISPR/Cas9

Aaron McKenna (University of Washington, USA)

16:40 - 17:10
S4-3
Polylox barcoding for tissue deconvolution

Hans-Reimer Rodewald (German Cancer Research Center, Germany)

 Invited speakers go to dinner

17:10 - 21:00


Wednesday, March 28, 2018 (Day 3)

 Session 5 :Chromosomal and Epigenetic Control

Chair: Wolf Reik

9:30 - 10:00
S5-1
Dissecting the higher-order chromatin organisation at single-cell resolution by single-cell Hi-C

Takashi Nagano (Babraham Institute, UK)

10:00 - 10:30
S5-2
Single-cell DNA replication timing profiling and the 3D genome organization dynamics during development

Ichiro Hiratani (RIKEN Center for Developmental Biology, Japan)

10:30 - 11:00
Coffee Break
11:00 - 11:30
S5-3
Elucidating the principles of cancer cell immortality using genetically defined human stem cell models

Dirk Hockemeyer (University of California, Berkeley, USA)

11:30 - 11:50
S5-4*
Dynamics and spatial genomics of single cells by intron seqFISH

Yodai Takei (California Institute of Technology, USA)

11:50 - 12:10
S5-5*
TBA

Yasuyuki Ohkawa (Kyushu University, Japan)

 Lunch and Poster Session 3

12:10 - 13:20
Free discussion, all posters

 Session 6: Aging

Chair: Hironobu Fujiwara

13:20 - 13:50
S6-1
Hypothalamic regulation of sleep and aging through mammalian sirtuins

Akiko Satoh (National Center for Geriatrics and Gerontology, Japan)

13:50 - 14:10
S6-2*
Defects in progeroid Cokayne syndrome are recapitulated during normal cellular senescence

Miria Ricchetti (Institut Pasteur, France)

14:10 - 14:30
Coffee Break
14:30 - 15:00
S6-3
Aging-induced dysregulation of intestinal stem cells in Drosophila

Sa Kan Yoo (RIKEN, Japan)

15:00 - 15:30
S6-4
TBA

Emmanuelle Passegué (Columbia University, USA)

15:30 - 16:00
S6-5
Transcriptional profiling of quiescent stem cells in vivo

Thomas Rando (Stanford University, USA)

 Closing Remarks

Benjamin D. Simons (University of Cambridge, UK)