How do chromosomes divide?

In a body, every single cell has the same number of chromosomes. This is because when a cell divides, the replicated chromatids are equally segregated into daughter cells. But, the first meiotic division is a clear exception. This division segregates maternal and paternal chromosomes for production of eggs and sperms, which are the origin of a new life. What is the story behind this division?

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News

9 August, 2017

The International Research Symposium on Regulation of Germ Cell Development in vivo and in vitro

Tomoya Kitajima was invited to present our research at the International Research Symposium on Regulation of Germ Cell Development in vivo and in vitro, held in Fukuoka from 26-28 July, 2017.


26 June, 2017

SMC Proteins 2017

Tomoya Kitajima was invited to present our research at the 2nd Meeting on SMC Proteins held in Nanyo from 13-16 June, 2017.


26 June, 2017

The Japan Society for Cell Biology

Shuhei Yoshida was invited to present our research at the 69th Annual Meeting of the Japan Society for Cell Biology held in Sendai from 13-15 June, 2017.


12 June, 2017

Gordon Research Seminar・EMBO Workshop 

Tomoya Kitajima was invited to present our research at Gordon Research Seminar, Chromosome Dynamics held in Lucca from 21 -26 May, 2017 and EMBO Workshop: Dynamic Kinetochore held in Edinburgh from 6-9 June, 2017.


9 May, 2017

A paper about a link between cytoplasmic size and chromosome segregation errors has been published.

The aneuploidy in eggs comes from chromosome segregation errors in oocytes. This paper provides experimental evidence that the uniquely large cytoplasm of the oocyte is linked to the error-prone chromosome segregation. The large cytoplasmic size of the oocyte may represent a trade-off between the fidelity of chromosome segregation and the potential to support post-fertilization embryogenesis.

Hirohisa Kyogoku & Tomoya S. Kitajima
Large cytoplasm is linked to the error-prone nature of oocytes.
Developmental Cell 41(3), 287-298 (2017)
doi: 10.1016/j.devcel.2017.04.009