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| Nobuaki Kikyo received his M.D.
in 1987 from the Faculty of Medicine, Tokyo University
and worked as a medical resident for two years before
entering the graduate school. He was awarded his Ph.D.
in 1993 from the same institution for his research on
the growth factors secreted from cancer cells. He then
worked as a postdoc on genetic imprinting under the supervision
of Dr. Azim Surani at the Wellcome/CRC Institute for Cancer
and Developmental Biology, University of Cambridge from
1994 to 1997. Inspired by Drs. Surani and Anne McLaren,
he made the mechanistic analysis of totipotency in early
embryonic cells as his long term research goal. He moved
to late Dr. Alan Wolffefs laboratory at the NIH in
1997 to study the reprogramming of somatic nuclei in Xenopus
egg extract as a model for somatic cell nuclear cloning,
one of the best experimental systems for the study of
totipotency. In 2000 he was recruited as an assistant
professor in the newly established Stem Cell Institute
at the University of Minnesota, to pursue the study of
cloning. His research focus is to understand how differentiated
somatic nuclei dedifferentiate and acquire totipotency
in egg cytoplasm. More specifically, his group is studying
the disassembly and reassembly of the nucleolus in the
context of nuclear cloning. |
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