Seminars and Events

Past Events

Category Seminar
Date and Time 2007-12-18 16:00 - 17:00
Venue Auditorium C1F
Speaker Daniel B. Forger III
Affiliation University of Michigan
Title Modeling Mammalian Circadian Rhythms
Poster click here to download(PDF)
Host Hiroki Ueda
Summary Biological circadian (~24-hour) clocks time many biological processes that must occur at specific times of the day. Circadian behavior in mammals is co-ordinated by a group of ~20,000 neurons in the suprachiasmatic nucleus (SCN). The molecular basis for these clock within each SCN neuron is a complex network of genetic feedback loops. I will use mathematical modeling to determine why ~24-hour oscillations appear in this network and what parts of the network determine the period. I will also present models of the SCN to determine how timkeeping is co-ordinated throughout the body.
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