Seminars and Events

Past Events

Category Seminar
Date and Time 2017-11-09 16:00 - 17:00
Venue Seminar Room A7F
Speaker Sophie Vriz
Affiliation Professor University Paris 7 - Denis Diderot
Title Redox signalling in development and regeneration
Poster click here to download(PDF)
Host Sa-Kan Yoo
Summary Reactive Oxygen Species (ROS) have long been considered toxic compounds. However, recent findings have shown that ROS contribute to bona fide physiological processes, leading to a new paradigm in reversible post translational modifications involved in signal transduction, known as redox signalling. We have developed genetic and optogenetic tools to record and manipulate H2O2 levels during zebrafish development and regeneration. This approach reveals an unexpected relationship between nerve, H2O2 and Shh signalling in morphogenesis and regeneration.